Portal vein embolization (PVE) is a recommended treatment performed prior to liver resection surgery to enlarge the liver segments that will remain following surgery. By obstructing the blood supply from the portal vein to the liver's damaged area, portal vein is a major blood supply to the liver, this procedure reroutes blood flow to the liver's remaining portion following surgery. This obstruction promotes the non-embolized healthy liver segment's growth while the embolized, diseased liver section begins to shrink. PVE improves one's odds of being a good candidate for liver cancer surgical excision. It can also reduce complications and shorten the length of stay in the hospital after liver resection surgery.
Usually, the procedure is performed as a single day admission procedure and surgery is usually planned 3-4 weeks after the procedure. Portal Vein Embolization does carry some side effects though. These include fever, nausea and vomiting, exhaustion, abdominal pain, bleeding or infection, and embolization material causing non targeted embolization. Most of these negative effects are prevented or relieved by medication.
Portal vein embolization has the following advantages:
Portal vein embolization is essential for improving the results of surgical treatments for patients with liver cancer as it encourages liver regeneration and creates a room for sufficient liver remnant.
The primary use of portal vein embolization (PVE) is to control advanced or metastatic liver cancer, including HCC , intrahepatic cholangiocarcinoima and resectable liver metastases in surgical candidates. PVE is used to improve the likelihood of entirely removing the diseased area of the liver during surgery, reduce problems associated with liver resection surgery, and shorten the hospital stay thereafter.
Patients with primary liver cancer (hepatocellular carcinoma) and colorectal liver metastases who require a scheduled hepatic resection are the best candidates for portal vein embolization (PVE). To be considered for surgery, these patients must still have a enough functional liver after the operation. The liver has the ability to recover after surgery, termed "hypertrophy," however this regeneration requires a minimum level of liver reserve. Surgeons can safely remove up to 70% of the liver and predict complete regeneration if the patient does not have major underlying liver disease, such as cirrhosis.
If the residual liver reserve (liver remnant) is insufficient to enable liver regeneration, portal vein embolization is performed to stimulate the remnant's regrowth before surgery.
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Know morePortal vein embolization (PVE) is a preoperative procedure used to induce hypertrophy (growth) of the liver. By blocking blood flow to certain segments of the liver, PVE encourages the remaining liver segments to grow, making surgery safer and more effective.
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